Generation of an induced pluripotent stem cell lines HMSCASTi001-A from peripheral blood mononuclear cells of a 35-year-old healthy male
Summary
Peripheral blood mononuclear cells derived from a 35-year-old healthy male were reprogrammed into induced pluripotent stem cells (iPSCs). The iPSCs maintained a normal karyotype, expressed various pluripotency stem cell markers, and showed potential of differentiating into three germ layers. This iPSCs could be differentiated into multiple cell subtypes for drug discovery and investigation of mechanisms. Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
Authors | Zhang Z, Liu J, Zhang J, Xian X, Hao P, Zhai Y, Cheng J, Yue F, Luan F, Ma M, Ren Q |
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Journal | Stem cell research |
Publication Date | 2022 Oct;64:102908 |
PubMed | 36113356 |
DOI | 10.1016/j.scr.2022.102908 |