Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma


Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies. Copyright © 2022. Published by Elsevier B.V.

Authors Kim JH, Hong JH, Kang KW, Lee BH, Park Y, Kim BS
Journal Stem cell research
Publication Date 2022 Dec;65:102939
PubMed 36332466
DOI 10.1016/j.scr.2022.102939

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