Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma
Summary
Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies. Copyright © 2022. Published by Elsevier B.V.
| Authors | Kim JH, Hong JH, Kang KW, Lee BH, Park Y, Kim BS |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Dec;65:102939 |
| PubMed | 36332466 |
| DOI | 10.1016/j.scr.2022.102939 |