Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual

Summary

A human induced pluripotent stem cell (hiPSC) line, KSCBi017-A, was generated from a 50-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank. Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Sam Im Y, Hoon Yoo D, Kim HE, Young Oh J, Kim YO
Journal Stem cell research
Publication Date 2022 Nov 11;65:102965
PubMed 36403547
DOI 10.1016/j.scr.2022.102965

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