Generation of integration-free induced pluripotent stem cell line (KSCBi017-A) from peripheral blood mononuclear cells of a healthy male individual
Summary
A human induced pluripotent stem cell (hiPSC) line, KSCBi017-A, was generated from a 50-year-old male individual using non-integrating episomal vectors expressing reprogramming factors. The generated hiPSCs were integration-free, expressed pluripotency markers, exhibited the potential for differentiation into three germ layers in vivo, and maintained the normal karyotype. This cell line can be used as a control for a disease model and is available from Korea National Stem Cell Bank. Copyright © 2022 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Sam Im Y, Hoon Yoo D, Kim HE, Young Oh J, Kim YO |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2022 Dec;65:102965 |
| PubMed | 36403547 |
| DOI | 10.1016/j.scr.2022.102965 |