iPS cells from Chediak-Higashi syndrome patients recapitulate the giant granules in myeloid cells
Summary
We succeeded in reproducing a characteristic cellular phenotype, giant granules in myeloid cells, using CHS-iPSCs, demonstrating that iPSCs can be used to model the pathogenesis of CHS patients. © 2022 Japan Pediatric Society.
| Authors | Oh S, Niwa A, Nagahashi A, Asaka I, Nakahata T, Saito MK |
|---|---|
| Journal | Pediatrics international : official journal of the Japan Pediatric Society |
| Publication Date | 2022 Jan;64(1):e15390 |
| PubMed | 36259166 |
| DOI | 10.1111/ped.15390 |