Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury
Summary
Our optogenetic approach demonstrates that transplanted cardiomyocytes can actively participate in heart function, supporting the hypothesis that the delivery of new force-generating myocardium can serve as a regenerative therapeutic strategy.
| Authors | Stüdemann T, Rössinger J, Manthey C, Geertz B, Srikantharajah R, von Bibra C, Shibamiya A, Köhne M, Wiehler A, Wiegert JS, Eschenhagen T, Weinberger F |
|---|---|
| Journal | Circulation |
| Publication Date | 2022 Oct 11;146(15):1159-1169 |
| PubMed | 36073365 |
| PubMed Central | PMC9555755 |
| DOI | 10.1161/circulationaha.122.060124 |