Generation of an induced pluripotent stem cell line (FDCHi008-A) from an infant with chronic intestinal pseudo-obstruction


Chronic intestinal pseudo-obstruction (CIPO) is a rare condition characterized by intestinal obstruction without any restriction or occlusion, that represents the most severe form of gastrointestinal dysmotility. Here we established the induced pluripotent stem cell line FDCHi008-A from PBMCs of a 4-month infant with CIPO, which provides a patient-specific in vitro model to explore the underlying pathogenesis of pediatric intestinal pseudo-obstruction. Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Liang H, Zhu W, Shen C, Zhu H
Journal Stem cell research
Publication Date 2023 Apr;68:103042
PubMed 36842377
DOI 10.1016/j.scr.2023.103042

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