Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer
Summary
Patient-derived human induced pluripotent stem cells (iPSCs) provide a potentially useful resource for studying disease pathology and therapeutics. In this study, we generated the breast cancer patient-derived KRIBBi009-A-iPSC line from normal fibroblasts using the Sendai virus, which expressed pluripotent markers and exhibited differentiation capacity across 3 germ layers through in vitro differentiation and in vivo teratoma assay. A normal karyotype and the absence of cross-contamination of the cell lines were confirmed. Consequently, the developed iPSC line has been confirmed to be suitable for use in various studies. Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Son N, Son YS, Jung CR, Son MY |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2023 Apr;68:103060 |
| PubMed | 36925228 |
| DOI | 10.1016/j.scr.2023.103060 |