Derivation of induced pluripotent stem cell SJTUi003-A from a 69-year-old Chinese Han Sporadic Alzheimer's disease patient with APOEε3/ε4 genetic background
Summary
Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disease. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 69-year-old female patient carrying APOEε3/ε4 allele and diagnosed with sporadic AD. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms and for drug tests in AD. Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Li H, Zhang B, Shi Z, Wu H, Mei S, Ai T, Shi A, Wang L, Zhu M, Tang J |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2023 Sep;71:103142 |
| PubMed | 37343430 |
| DOI | 10.1016/j.scr.2023.103142 |