Establishment of induced pluripotent stem cell line SDPHi003-A from a healthy male donor


Peripheral blood mononuclear cells (PBMCs) were derived from a 67-year-old Chinese male. We used non-integrating episomal vectors containing OCT4, SOX2, KLF4 and c-MYC to reprogram PBMCs into induced pluripotent stem cell (iPSCs). This iPSC line, SDPHi003-A, have a normal karyotype, expressed pluripotent markers and have the potential for trilineage differentiation. This iPSC line can be used as a control for disease modeling studies and contribute to the research exploring disease pathogenesis. Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Xi Y, Zhang H, Yang X, Ai D, Liu Y, Song W
Journal Stem cell research
Publication Date 2023 Sep;71:103160
PubMed 37429069
DOI 10.1016/j.scr.2023.103160

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