Establishment of induced pluripotent stem cell line SDPHi003-A from a healthy male donor
Summary
Peripheral blood mononuclear cells (PBMCs) were derived from a 67-year-old Chinese male. We used non-integrating episomal vectors containing OCT4, SOX2, KLF4 and c-MYC to reprogram PBMCs into induced pluripotent stem cell (iPSCs). This iPSC line, SDPHi003-A, have a normal karyotype, expressed pluripotent markers and have the potential for trilineage differentiation. This iPSC line can be used as a control for disease modeling studies and contribute to the research exploring disease pathogenesis. Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Xi Y, Zhang H, Yang X, Ai D, Liu Y, Song W |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2023 Sep;71:103160 |
| PubMed | 37429069 |
| DOI | 10.1016/j.scr.2023.103160 |