A resource for cell line authentication, annotation and quality control
Summary
Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for cell line annotation linked to short tandem repeat and single nucleotide polymorphism profiles, and provide a catalogue of synonymous cell lines. This resource will enable our community to eradicate the use of misidentified lines and generate credible cell-based data.
| Authors | Yu M, Selvaraj SK, Liang-Chu MM, Aghajani S, Busse M, Yuan J, Lee G, Peale F, Klijn C, Bourgon R, Kaminker JS, Neve RM |
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| Journal | Nature |
| Publication Date | 2015 Apr 16;520(7547):307-11 |
| PubMed | 25877200 |
| DOI | 10.1038/nature14397 |
Research Projects
Cell Lines
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