HLA-based banking of induced pluripotent stem cells in Saudi Arabia
Summary
Our study sets a road map for introducing iPS-based cell therapy in the Kingdom of Saudi Arabia. It underscores the pragmatic approach of HLA-based iPSC banking which circumvents the limitations of autologous iPS-based cellular therapies. The successful generation and validation of iPSC lines based on the most prevalent HLA haplotype in the Saudi population signify a promising step toward broadening the accessibility and applicability of stem cell therapies and regenerative medicine in Saudi Arabia. © 2023. The Author(s).
| Authors | Alowaysi M, Lehmann R, Al-Shehri M, Baadhaim M, Alzahrani H, Aboalola D, Zia A, Malibari D, Daghestani M, Alghamdi K, Haneef A, Jawdat D, Hakami F, Gomez-Cabrero D, Tegner J, Alsayegh K |
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| Journal | Stem cell research & therapy |
| Publication Date | 2023 Dec 18;14(1):374 |
| PubMed | 38111036 |
| PubMed Central | PMC10729375 |
| DOI | 10.1186/s13287-023-03612-0 |