Generation of a control iPS cell line (JUCGRMi005-A) with no abnormalities in Parkinson's disease-related genes
Summary
Appropriate control induced pluripotent stem cells (iPSCs) are essential for studying iPSCs derived from patients with Parkinson's disease (PD). In this study, we established an iPSC line from a healthy male donor. The iPSCs showed pluripotency, capacity to differentiate into three germ layers, and normal karyotypes. Additionally, we confirmed that the iPSC line did not exhibit any PD-related gene abnormalities. This iPSC line will be useful for PD research. Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Ishikawa KI, Shiga T, Funayama M, Hattori N, Akamatsu W |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2024 Feb;74:103271 |
| PubMed | 38100917 |
| DOI | 10.1016/j.scr.2023.103271 |