Generation of a control iPS cell line (JUCGRMi006-A) with no abnormalities in Parkinson's disease-related genes

Summary

The appropriate control of induced pluripotent stem cells (iPSCs) is essential for studying iPSCs derived from patients with Parkinson's disease (PD). Here, we established an iPSC line from a healthy female donor. The iPSCs were pluripotent, could differentiate into three germ layers, and had normal karyotypes. We also confirmed that the iPSC line exhibited no PD-related gene abnormalities. This iPSC line will be useful for PD research. Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Ishikawa KI, Shiga T, Funayama M, Hattori N, Akamatsu W
Journal Stem cell research
Publication Date 2024 Feb;74:103270
PubMed 38100911
DOI 10.1016/j.scr.2023.103270

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