Induced pluripotent stem cell derived pericytes respond to mediators of proliferation and contractility


iPericytes express pericyte-associated genes and proteins and, exhibit an appropriate physiological response upon exposure to a key endogenous mitogen or vasoactive mediators. Therefore, the generation of functional iPericytes would be suitable for use in future investigations exploring pericyte function or dysfunction in neurological diseases. © 2024. The Author(s).

Authors King NE, Courtney JM, Brown LS, Fortune AJ, Blackburn NB, Fletcher JL, Cashion JM, Talbot J, Pébay A, Hewitt AW, Morris GP, Young KM, Cook AL, Sutherland BA
Journal Stem cell research & therapy
Publication Date 2024 Mar 3;15(1):59
PubMed 38433209
PubMed Central PMC10910734
DOI 10.1186/s13287-024-03671-x

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