Differential lipolytic regulation in human embryonic stem cell-derived adipocytes


Although hESC-derived adipocytes seem to be morphologically and expressionally similar to mature adipocytes, there are important functional differences that could depend on their early developmental origin. We conclude that, in contrast to mature adipocytes, hESC-derived adipocytes display a differential response to atrial natriuretic peptide and catecholamines.

Authors van Harmelen V, Aström G, Strömberg A, Sjölin E, Dicker A, Hovatta O, Rydén M
Journal Obesity (Silver Spring, Md.)
Publication Date 2007 Apr;15(4):846-52
PubMed 17426319
DOI 10.1038/oby.2007.595

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