Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservation
Summary
Together, an entirely matrix-free, highly efficient, flexible and automation-friendly hPSC expansion strategy is demonstrated, facilitating the development of good manufacturing practice-compliant closed-system manufacturing in large scale. © 2024. The Author(s).
| Authors | Ullmann K, Manstein F, Triebert W, Kriedemann N, Franke A, Teske J, Mertens M, Lupanow V, Göhring G, Haase A, Martin U, Zweigerdt R |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2024 Mar 25;15(1):89 |
| PubMed | 38528578 |
| PubMed Central | PMC10964510 |
| DOI | 10.1186/s13287-024-03699-z |