Generation of a human iPSC cell line (MUSIi017-A) from a donor with O negative blood type
Summary
The Rh-negative type O blood group (O Rh-) is considered a universal donor for emergency blood transfusions. Due to the constant shortage of this rare blood group, the production of blood cells from iPSCs derived from the O Rh- donor could potentially serve as a limitless blood source for transfusions. In this report, we establish a MUSIi017-A iPSC line from peripheral blood mononuclear cells of a healthy donor with the O Rh- blood group. The established iPSC line exhibited a normal karyotype, showed identical STR compared to donor peripheral blood mononuclear cells, and could differentiate to all three germ layers. Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Jiamvoraphong N, Lorthongpanich C, Klaihmon P, Kheolamai P, Issaragrisil S |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2024 Aug;78:103466 |
| PubMed | 38852425 |
| DOI | 10.1016/j.scr.2024.103466 |