Generation of an iPSC line from a 79-year-old female patient diagnosed with sporadic Parkinson's disease
Summary
Parkinson's disease is a common neurodegenerative disorder. Here we present a human induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female patient diagnosed with sporadic Parkinson's disease using the sendai virus. Generated iPSCs maintain normal karyotype, exhibit pluripotent stem cell markers, and possess differentiation potential. The iPSCs allows for differentiation into various cell subtypes, providing conditions for the research of the pathogenesis and drug development of Parkinson's disease. Copyright © 2024. Published by Elsevier B.V.
| Authors | Liu J, Du J, Ma X, Jin Y, Yang Q, Zhai Y, Cheng J, Luan F, Ma M, Zhang Z, Ren Q, Cui H |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2024 Aug;78:103450 |
| PubMed | 38820865 |
| DOI | 10.1016/j.scr.2024.103450 |