Establishment of an induced pluripotent stem cell (iPSC) line (JNMUi002-A) from a male patient with schizophrenia
Summary
We obtained Peripheral blood mononuclear cells (PBMCs) from a peripheral blood sample of a 19-year-old male schizophrenia patient and successfully established induced pluripotent stem cell (iPSC) line using non-integrated reprogramming technology. This cell line possesses the correct karyotype, shape of an embryonic stem cell, the ability to express particular pluripotency markers, and the capacity to differentiate into three germ layers in vitro. This cell line will serve as an in vitro model for upcoming studies on the etiology of schizophrenia and the creation of novel treatment. Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Jiang M, Long Y, Liu Y, Li R, Xu J, Chi T, Sun M, Li M, Yu H, Yu L, Han X |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2024 Dec;81:103570 |
| PubMed | 39368271 |
| DOI | 10.1016/j.scr.2024.103570 |