Establishing an induced pluripotent stem cell line (SDPHi006-A) from a healthy Chinese female donor represents an accomplishment
Summary
We isolated peripheral blood mononuclear cells (PBMCs) from a healthy female donor, and successfully converted into induced pluripotent stem cells (iPSCs) by using non-integrating episomal vectors. These iPSCs displayed a normal karyotype, expressed markers of pluripotency, and showed the capacity to differentiate into three germ layers in vitro, which could be utilized for future research endeavors. Copyright © 2024. Published by Elsevier B.V.
| Authors | Shao J, Shao C, Yang G, Jin Y |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2024 Dec;81:103590 |
| PubMed | 39454534 |
| DOI | 10.1016/j.scr.2024.103590 |