Mutated LRRK2 induces a reactive phenotype and alters migration in human iPSC-derived pericyte-like cells
Summary
In summary, our findings support the notion that pericytes play a role in the inflammatory and vascular changes observed in PD. Further investigation of pericytes could provide valuable insight into understanding the pathogenesis of PD. © 2024. The Author(s).
| Authors | Peltonen S, Sonninen TM, Niskanen J, Koistinaho J, Ruponen M, Lehtonen Š |
|---|---|
| Journal | Fluids and barriers of the CNS |
| Publication Date | 2024 Nov 18;21(1):92 |
| PubMed | 39551752 |
| PubMed Central | PMC11571670 |
| DOI | 10.1186/s12987-024-00592-y |