Human liver organoids are susceptible to Plasmodium vivax infection
Summary
Stem cell-derived liver organoids resemble mature liver cells in terms of liver functions and are susceptible to infection with P. vivax sporozoites, paving the way for studies on the mechanism of hypnozoite formation and testing of possible hypnozoitocidal drugs. © 2024. The Author(s).
| Authors | Nitaramorn N, Kobpornchai P, Tongkrajang N, Chaisri U, Imwong M, Kulkeaw K |
|---|---|
| Journal | Malaria journal |
| Publication Date | 2024 Dec 5;23(1):368 |
| PubMed | 39639330 |
| PubMed Central | PMC11622667 |
| DOI | 10.1186/s12936-024-05202-8 |