Current advancements in nanotechnology for stem cells
Summary
Stem cell therapy has emerged as a promising approach for regenerative medicine, offering potential treatments for a wide range of diseases and injuries. Although stem cell therapy has great promise, several obstacles have prevented its broad clinical adoption. The effectiveness of therapy has been inhibited by problems such as ineffective stem cell differentiation, low post-transplantation survival rates, and restricted control over stem cell behaviour. Furthermore, the implementation of stem cell therapies is further complicated by the possibility of immunological rejection and cancer. Innovative strategies that provide precise control over stem cell characteristics and maximize their therapeutic potential are desperately needed to overcome these obstacles. Recent studies have shown that the effectiveness of stem cell treatments can be greatly increased by nanoscale advances. By establishing an ideal microenvironment and precisely offering growth factors, nanomaterials such as nanoparticles, nanocomposites, and quantum dots have been demonstrated to improve stem cell differentiation and proliferation. This article provides an overview of the recent trends and applications of nanoscale innovations in the context of stem cell therapy. The recent development of precision medicine has been facilitated by the incorporation of nanotechnology into stem cell therapy. The ability to manipulate stem cells at the nanoscale offers unprecedented control over their behavior and function, opening up exciting possibilities for personalized and highly effective therapeutic interventions. This review paper highlights the recent trends and applications of nanotechnology in advancing stem cell therapy, showcasing its potential to revolutionize regenerative medicine. Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.
| Authors | Thamarai P, Karishma S, Kamalesh R, Shaji A, Saravanan A, Bibi S, Vickram AS, Chopra H, Saleem RA, Alsharif KF, Theyab A, Kamel M, Alamoudi MK, Kumer A, Chopra S, Abdel-Daim MM |
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| Journal | International journal of surgery (London, England) |
| Publication Date | 2024 Sep 5;110(12):7456-76 |
| PubMed | 39236089 |
| PubMed Central | PMC11634102 |
| DOI | 10.1097/js9.0000000000002082 |