Derivation of induced pluripotent stem cell FDZSi002-A from a 67-year-old Chinese Han Prostate cancer patient

Summary

Prostate cancer (PCa) is the most common malignant tumor of the male reproductive system. In this study, we generated an induced pluripotent stem cell (iPSC) line from the peripheral blood mononuclear cells (PBMCs) of a 67-year-old male patient and diagnosed with PC. The established iPSCs were confirmed by flow cytometry and immunofluorescence. Furthermore, the iPSC line has a normal chromosomal karyotype and has the potential of spontaneous differentiation into three germ layers in vitro. The iPSC line will be a useful tool for investigating the pathogenesis mechanisms of PCa. Copyright © 2025 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Hou CS, Zhu Z, Xie XF, Lu XQ, Chen Z, Cui HY, Wu H, Zhang B, Hou CS
Journal Stem cell research
Publication Date 2025 Jan 7;83:103659
PubMed 39854878
DOI 10.1016/j.scr.2025.103659

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