Generation of a human induced pluripotent stem cells line (JNMUi001-A) from peripheral blood mononuclear cells of a male patient with schizophrenia
Summary
We collected a blood sample from a 35-year-old male diagnosed with schizophrenia, isolated peripheral blood mononuclear cells, and generated a human induced pluripotent stem cells (hiPSCs) line using non-integrative reprogramming techniques. The derived cells exhibit characteristics typical of embryonic stem cells, are capable of expressing specific pluripotency markers, and can differentiate into all three embryonic layers in vitro. This iPSCs line serves as an in vitro model for investigating disease mechanisms and for developing novel therapeutic approaches. Copyright © 2025. Published by Elsevier B.V.
| Authors | Long Y, Jiang M, Liu Y, Li R, Xu J, Chi T, Sun M, Li M, Yu H, Han X |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2025 Feb 11;84:103680 |
| PubMed | 39961164 |
| DOI | 10.1016/j.scr.2025.103680 |