Endoplasmic reticulum stress and rhodopsin accumulation in an organoid model of Retinitis Pigmentosa carrying a RHO pathogenic variant
Summary
Unraveling the molecular pathophysiology of these mutations is key for understanding the basis of the disease and design proper gene and cell therapies for its treatment. © 2025. The Author(s).
| Authors | Navinés-Ferrer A, Pomares E |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2025 Feb 14;16(1):71 |
| PubMed | 39948682 |
| PubMed Central | PMC11827366 |
| DOI | 10.1186/s13287-025-04199-4 |