Endoplasmic reticulum stress and rhodopsin accumulation in an organoid model of Retinitis Pigmentosa carrying a RHO pathogenic variant

Summary

Unraveling the molecular pathophysiology of these mutations is key for understanding the basis of the disease and design proper gene and cell therapies for its treatment. © 2025. The Author(s).

Authors Navinés-Ferrer A, Pomares E
Journal Stem cell research & therapy
Publication Date 2025 Feb 14;16(1):71
PubMed 39948682
PubMed Central PMC11827366
DOI 10.1186/s13287-025-04199-4

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