Endoplasmic reticulum stress and rhodopsin accumulation in an organoid model of Retinitis Pigmentosa carrying a RHO pathogenic variant
Summary
Unraveling the molecular pathophysiology of these mutations is key for understanding the basis of the disease and design proper gene and cell therapies for its treatment. © 2025. The Author(s).
Authors | Navinés-Ferrer A, Pomares E |
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Journal | Stem cell research & therapy |
Publication Date | 2025 Feb 14;16(1):71 |
PubMed | 39948682 |
PubMed Central | PMC11827366 |
DOI | 10.1186/s13287-025-04199-4 |