Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols
Summary
Taken together, our results provide a systematic description of cilia in hiPSC-derived neuronal cells generated with different protocols, underscoring the importance of selecting the optimal model system and controls for investigating primary cilia in hiPSC-derived neuronal cells. Copyright © 2025 Haenseler, Eschment, Evans, Brasili, Figueiro-Silva, Roethlisberger, Abidi, Jackson, Müller, Cowley and Bachmann-Gagescu.
| Authors | Haenseler W, Eschment M, Evans B, Brasili M, Figueiro-Silva J, Roethlisberger F, Abidi A, Jackson D, Müller M, Cowley SA, Bachmann-Gagescu R |
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| Journal | Frontiers in cell and developmental biology |
| Publication Date | 2025;13:1516596 |
| PubMed | 40292331 |
| PubMed Central | PMC12021924 |
| DOI | 10.3389/fcell.2025.1516596 |