Circular RNAs increase during vascular cell differentiation and are biomarkers for vascular disease
Summary
Time-resolved transcriptional profiling of linear and circRNA species revealed that circRNAs provide granular molecular information for disease profiling. The identified circRNAs may serve as blood biomarkers for atherosclerotic vascular disease. © The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology.
| Authors | Northoff BH, Herbst A, Wenk C, Weindl L, Gäbel G, Brezski A, Zarnack K, Küpper A, Dimmeler S, Moretti A, Laugwitz KL, Engelhardt S, Maegdefessel L, Boon RA, Doppler S, Dreßen M, Lahm H, Lange R, Krane M, Krohn K, Kohlmaier A, Holdt LM, Teupser D |
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| Journal | Cardiovascular research |
| Publication Date | 2025 Apr 29;121(3):405-423 |
| PubMed | 39901821 |
| PubMed Central | PMC12038242 |
| DOI | 10.1093/cvr/cvaf013 |