Overall survival among patients with activated phosphoinositide 3-kinase delta syndrome (APDS)

Summary

Reduced survival in patients with APDS suggests a high disease burden, particularly in those with concurrent lymphoma. These results highlight the unmet need for disease-modifying treatments for APDS. © 2025. The Author(s).

Authors Mahendran M, Upton JEM, Ramasubramanian R, Memmott HL, Germain G, Büsch K, Laliberté F, Harrington A
Journal Orphanet journal of rare diseases
Publication Date 2025 May 3;20(1):212
PubMed 40319290
PubMed Central PMC12049806
DOI 10.1186/s13023-025-03734-z

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