Cold receptor TRPM8 as a target for migraine-associated pain and affective comorbidities

Summary

Together, our findings underscore the potential of TRPM8 for migraine relief and its involvement in affective comorbidities, emphasizing the importance of addressing emotional symptoms to improve clinical outcomes for migraine sufferers, especially in females. © 2025. The Author(s).

Authors Cabañero D, Carter EP, González-Cano R, Cobos EJ, Fernández-Carvajal A, Ferrer-Montiel A
Journal The journal of headache and pain
Publication Date 2025 Jun 23;26(1):146
PubMed 40545528
PubMed Central PMC12183901
DOI 10.1186/s10194-025-02082-4

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