Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene
Summary
Here, we report the establishment of a human induced pluripotent stem cell (hiPSC) line TUR-STAB1-B1 derived from peripheral blood mononuclear cells of a patient carrying heterozygous mutations 52,509,890 C>A 790L>I and 52,520,515 G>A 1872R>H on STAB1 gene in addition to a normal control cell line TUR-B1. The pluripotency, identity, quality, safety, and sequence of the mutation sites of the cell lines were confirmed. The generated patient-specific cell line will facilitate detailed studies of the STAB1 in various differentiated cell types. Copyright © 2025. Published by Elsevier B.V.
| Authors | Sandelin S, Giannareas N, Seppänen MRJ, Kere J, Hollmén M, Närvä E |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2025 Jun 2;87:103750 |
| PubMed | 40482634 |
| DOI | 10.1016/j.scr.2025.103750 |