Generation of human induced pluripotent stem cell lines from healthy Korean donors (IPBi101-A, IPBi102-A, IPBi103-A, IPBi105-A, IPBi107-A, IPBi108-A, IPBi110-A, IPBi111-A, IPBi113-A, and IPBi114-A)
Summary
Human induced pluripotent stem cell (iPSC) lines were derived from peripheral blood mononuclear cells (PBMCs) obtained from ten healthy Korean donors of diverse ages and genders using a Sendai virus-based reprogramming method. These iPSC lines expressed markers of undifferentiated state and demonstrated trilineage differentiation potential in vitro. Characterization confirmed normal karyotypes, clearance of the Sendai virus, and short tandem repeat (STR) profiles identical to the parental PBMCs. These cell lines can serve as a valuable resource for disease modeling, drug screening, and as a human-based alternative to animal experiments. Copyright © 2025. Published by Elsevier B.V.
| Authors | Lee M, Park J, Kim YE, Nah S, Han M, Heo CY, Nakanishi M, Song J |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2025 Aug 27;88:103821 |
| PubMed | 40885024 |
| DOI | 10.1016/j.scr.2025.103821 |