Generation of human induced pluripotent stem cell lines from healthy Korean donors (IPBi101-A, IPBi102-A, IPBi103-A, IPBi105-A, IPBi107-A, IPBi108-A, IPBi110-A, IPBi111-A, IPBi113-A, and IPBi114-A)

Summary

Human induced pluripotent stem cell (iPSC) lines were derived from peripheral blood mononuclear cells (PBMCs) obtained from ten healthy Korean donors of diverse ages and genders using a Sendai virus-based reprogramming method. These iPSC lines expressed markers of undifferentiated state and demonstrated trilineage differentiation potential in vitro. Characterization confirmed normal karyotypes, clearance of the Sendai virus, and short tandem repeat (STR) profiles identical to the parental PBMCs. These cell lines can serve as a valuable resource for disease modeling, drug screening, and as a human-based alternative to animal experiments. Copyright © 2025 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Lee M, Park J, Kim YE, Nah S, Han M, Heo CY, Nakanishi M, Song J
Journal Stem cell research
Publication Date 2025 Oct;88:103821
PubMed 40885024
DOI 10.1016/j.scr.2025.103821

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