Induced pluripotent stem cells carrying novel APTX mutations presented defective neural differentiation with the accumulation of DNA single-strand breaks

Authors Chen Zirui, Huang Yihua, Yuan Zhirong, Xu Kaibiao, Guan Yuqing, Wang Luqin, Jiang Yawei, Deng Weiling, Pan Yue, Liu Jing, Hu Yafang
Journal Cell Death Discovery
Publication Date 2025-10-24
DOI 10.1038/s41420-025-02723-2

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