Transcriptome profiling of bovine inner cell mass and trophectoderm derived from in vivo generated blastocysts
Summary
The transcriptional changes occur during ICM and TE lineages specification in bovine is greater than previously understood. Therefore, this array data establishes a standard to evaluate the in vitro imprint on the transcriptome and to hypothesize the cross-species differences that allow in vitro acquisition of pluripotent ICM in human and mice but hinder that process in bovine.
| Authors | Hosseini SM, Dufort I, Caballero J, Moulavi F, Ghanaei HR, Sirard MA |
|---|---|
| Journal | BMC developmental biology |
| Publication Date | 2015 Dec 18;15:49 |
| PubMed | 26681441 |
| PubMed Central | PMC4683974 |
| DOI | 10.1186/s12861-015-0096-3 |