Generation of an induced pluripotent stem cell line CGOi001-A from a patient with hereditary thrombocytopenia and a germline ANKRD26 mutation

Summary

Thrombocytopenia 2 (OMIM 610855) is a hereditary thrombocytopenia and blood cancer syndrome caused by germline mutations in the 5' untranslated region of ANKRD26. We generated an induced pluripotent stem cell (iPSC) line (CGOi001-A) from a donor with a germline ANKRD26 mutation and hereditary thrombocytopenia. This line is a valuable resource for studying the ANKRD26-mutant cellular phenotype. Copyright © 2026 The Author(s). Published by Elsevier B.V. All rights reserved.

Authors Ramsland AS, Dudek K, McNeely KE, Cannova JM, Khosravi Z, Burnett J, Gilad Y, Godley LA, Griffiths EA, Drazer MW
Journal Stem cell research
Publication Date 2026 Mar;91:103919
PubMed 41643484
DOI 10.1016/j.scr.2026.103919

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