Defined culture conditions improve functional properties of mature iPSC-derived macrophages for therapeutic screening
Summary
The enhanced responsiveness to co-stimulatory signals makes iPSC-Mac from defined cultures more suitable for testing immunomodulatory drugs, novel bio-assays and in vivo applications. © 2026. The Author(s).
| Authors | Schinke M, Gensch I, Rietschel T, Nguyen AHH, Slevogt H, Jänsch L, Lachmann N |
|---|---|
| Journal | Stem cell research & therapy |
| Publication Date | 2026 Apr 11;17(1) |
| PubMed | 41964059 |
| PubMed Central | PMC13078047 |
| DOI | 10.1186/s13287-026-05009-1 |