Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis
Summary
X-linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy manifested as splitting of anatomical layers of retina. In this report, we generated a patient-specific induced pluripotent stem cell (iPSC) line, TVGH-iPSC-013-05, from the peripheral blood mononuclear cells of a male patient with XLRS by using the Sendai-virus delivery system. We believe that XLRS patient-specific iPSCs provide a powerful in vitro model for evaluating the pathological phenotypes of the disease. Copyright © 2018. Published by Elsevier B.V.
| Authors | Peng CH, Huang KC, Lu HE, Syu SH, Yarmishyn AA, Lu JF, Buddhakosai W, Lin TC, Hsu CC, Hwang DK, Shen CN, Chen SJ, Chiou SH |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2018 May;29:152-156 |
| PubMed | 29674172 |
| DOI | 10.1016/j.scr.2018.04.005 |