Generation and characterization of two iPSC lines INDBi002-A and INDBi002-B from human keratinocytes of a healthy female using Sendai Virus reprogramming
Summary
We established two fully characterized induced pluripotent stem cell (iPSC) lines from human keratinocytes via Sendai virus-mediated reprogramming. This non-integrating approach maintains genomic integrity, facilitating the generation of pluripotent cell lines with stable self-renewal and multilineage differentiation potential. Characterization confirmed the expression of stemness markers, the capacity for trilineage differentiation, and a normal karyotype. The iPSC lines are a valuable platform for applications in disease modeling, pharmacological screening, and regenerative medicine. Copyright © 2026 The Author(s). Published by Elsevier B.V. All rights reserved.
| Authors | Sperlich D, Becker K, Klingenstein S, Mau-Holzmann U, Liebau S, Achberger K |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2026 Aug 11;95:104075 |
| PubMed | 42594645 |
| DOI | 10.1016/j.scr.2026.104075 |