Generation of alveolar organoids from human induced pluripotent stem cells using a stirred-tank bioreactor
Summary
Pre- differentiation of iPSCs, e.g., in embryoid bodies seems to be a necessary prerequisite for the efficient generation of iPSC-LuOrgs, which then exhibit alveolar and bronchial cell types and structures supported by mesenchymal cells. Copyright © 2026 Budeus, Cremer, Sevindik and Klein.
| Authors | Budeus B, Cremer L, Sevindik ZF, Klein D |
|---|---|
| Journal | Frontiers in bioengineering and biotechnology |
| Publication Date | 2026;14:1858660 |
| PubMed | 42620978 |
| PubMed Central | PMC13485884 |
| DOI | 10.3389/fbioe.2026.1858660 |