Toward a cell-type-specific lung HOX code
Summary
Since the deregulation of HOX genes is increasingly observed in numerous (malignant) lung diseases, it is a necessary prerequisite to specify individual HOX factors and their cellular origin. This could not only provide better insights into the function of HOX genes in lung diseases but also offer the possibility of improving the regenerative potential through targeted modulation of (cell-type-specific) HOX genes. Copyright © 2026 Budeus and Klein.
| Authors | Budeus B, Klein D |
|---|---|
| Journal | Frontiers in cell and developmental biology |
| Publication Date | 2026;14:1839422 |
| PubMed | 42523700 |
| PubMed Central | PMC13407532 |
| DOI | 10.3389/fcell.2026.1839422 |