Chondrocytes differentiated from human induced pluripotent stem cells: Response to ionizing radiation
Summary
The chondrocyte-like cells derived from hiPSC demonstrated features characteristic of both mature chondrocytes and "parental" hiPSCs. The main difference between hiPSC-derived chondrocytes and hiPSCs and mature chondrocytes appears to be the more efficient DDR mechanism of hiPSC-DCHs. The unique properties of these cells suggest that they could potentially be used safely in regenerative medicine if these preliminary findings are confirmed in future studies.
| Authors | Stelcer E, Kulcenty K, Suchorska WM |
|---|---|
| Journal | PloS one |
| Publication Date | 2018;13(10):e0205691 |
| PubMed | 30352062 |
| PubMed Central | PMC6198947 |
| DOI | 10.1371/journal.pone.0205691 |