Generation of a human Ocular Albinism type 1 iPSC line, SEIi001-A, with a mutation in GPR143
Summary
Ocular albinism type 1 is a genetic eye disease caused by mutations in the GPR143 gene. Little is known about the molecular pathways involved in this disease and no therapeutic candidate has been identified as yet. Here we report the generation of an iPSC line from the skin fibroblasts of a patient with a mutation in the GPR143 gene using Sendai Virus vectors. This new iPSC line will allow a better understanding of the Ocular Albinism type 1 disease and to screen for potential therapeutic candidates. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Baulier E, Garcia Diaz A, Corneo B, Farber DB |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2018 Dec;33:274-277 |
| PubMed | 30513407 |
| DOI | 10.1016/j.scr.2018.11.016 |