Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia
Summary
Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Bai X, Yang X, Cheng Y, Chen L |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2019 Jan;34:101369 |
| PubMed | 30611020 |
| PubMed Central | PMC6441353 |
| DOI | 10.1016/j.scr.2018.101369 |