Establishment of an induced pluripotent stem cell line (FDEENTi001-A) from a patient with pathological myopia


Pathological myopia (PM) is a retinal degenerative disease with an increasing prevalence in Asia. The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. This line may provide a useful resource for exploring the pathogenesis of PM. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Bai X, Yang X, Cheng Y, Chen L
Journal Stem cell research
Publication Date 2019 Jan;34:101369
PubMed 30611020
PubMed Central PMC6441353
DOI 10.1016/j.scr.2018.101369

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