Transplantation of Human Embryonic Stem Cell-Derived Cardiovascular Progenitors for Severe Ischemic Left Ventricular Dysfunction
Summary
This trial demonstrates the technical feasibility of producing clinical-grade hESC-derived cardiovascular progenitors and supports their short- and medium-term safety, thereby setting the grounds for adequately powered efficacy studies. (Transplantation of Human Embryonic Stem Cell-derived Progenitors in Severe Heart Failure [ESCORT]; NCT02057900). Copyright © 2018 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
| Authors | Menasché P, Vanneaux V, Hagège A, Bel A, Cholley B, Parouchev A, Cacciapuoti I, Al-Daccak R, Benhamouda N, Blons H, Agbulut O, Tosca L, Trouvin JH, Fabreguettes JR, Bellamy V, Charron D, Tartour E, Tachdjian G, Desnos M, Larghero J |
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| Journal | Journal of the American College of Cardiology |
| Publication Date | 2018 Jan 30;71(4):429-438 |
| PubMed | 29389360 |
| DOI | 10.1016/j.jacc.2017.11.047 |
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