Establishment of an induced pluripotent stem cell line (FDEENTi002-A) from a patient with Best's disease carrying c.888C > A mutation in BEST1 gene
Summary
Best's disease (BD) is an inherited retinal degenerative disease caused by mutations in BEST1 gene. A human induced pluripotent stem cell (iPSC) line has been generated with integration-free Sendai virus method from peripheral blood mononuclear cells (PBMCs) of a BD patient carrying c.888C > A mutation in BEST1 gene. This cell line may serve as a model for the study of pathogenesis of BD. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Bai X, Yang XJ, Chen L |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2019 Jul;38:101459 |
| PubMed | 31146250 |
| PubMed Central | PMC7156156 |
| DOI | 10.1016/j.scr.2019.101459 |