Proteomic profiling of human embryonic stem cell-derived microvesicles reveals a risk of transfer of proteins of bovine and mouse origin
Summary
These findings indicate that MV represent a mechanism by which hESC communicate; however, they also serve as potential carriers of immunogenic and pathogenic compounds acquired from environment. Our results highlight a potential danger regarding the use of hESC that have previously been exposed to animal proteins and cells.
| Authors | Kubikova I, Konecna H, Sedo O, Zdrahal Z, Rehulka P, Hribkova H, Rehulkova H, Hampl A, Chmelik J, Dvorak P |
|---|---|
| Journal | Cytotherapy |
| Publication Date | 2009;11(3):330-40, 1 p following 340 |
| PubMed | 19401887 |
| DOI | 10.1080/14653240802595531 |