Proteomic profiling of human embryonic stem cell-derived microvesicles reveals a risk of transfer of proteins of bovine and mouse origin
These findings indicate that MV represent a mechanism by which hESC communicate; however, they also serve as potential carriers of immunogenic and pathogenic compounds acquired from environment. Our results highlight a potential danger regarding the use of hESC that have previously been exposed to animal proteins and cells.
|Authors||Kubikova I, Konecna H, Sedo O, Zdrahal Z, Rehulka P, Hribkova H, Rehulkova H, Hampl A, Chmelik J, Dvorak P|
|Publication Date||2009;11(3):330-40, 1 p following 340|