Generation of an integration-free human induced pluripotent stem cell line MUSIi010-A from occipital scalp fibroblasts of a male patient with androgenetic alopecia
Summary
An induced pluripotent stem cell (iPSC) line, MUSIi010-A, was established by Sendai virus (SeV) transduction of scalp fibroblasts from a 59-year-old male with androgenetic alopecia (AGA). Pluripotency of the iPSC line was verified by immunofluorescence staining of pluripotent markers and by in vitro trilineage differentiation. The MUSIi010-A line was shown to retain normal karyotype and free of SeV vectors at passage 17. This iPSC line can be used for studying pathological mechanisms of AGA. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Tantarungsee N, Bostan Ali Z, Soi-Ampornkul R, Rujitharanawong C, Subchookul C, Ritthaphai A, Boonkaew B, Wattanapanitch M, Thanomkitti K, Triwongwaranat D, Vatanashevanopakorn C, Thuangtong R |
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| Journal | Stem cell research |
| Publication Date | 2019 Jul;38:101486 |
| PubMed | 31228683 |
| DOI | 10.1016/j.scr.2019.101486 |