Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors
Summary
In conclusion, the results show a significant effect of the inoculum density on cell expansion, differentiation and production of hiPSCs, emphasizing the importance of the inoculum density for downstream applications of hiPSCs. Furthermore, the bioreactor technology was successfully applied for controlled and scalable production of hiPSCs for clinical use. © 2019 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.
| Authors | Greuel S, Hanci G, Böhme M, Miki T, Schubert F, Sittinger M, Mandenius CF, Zeilinger K, Freyer N |
|---|---|
| Journal | Cell proliferation |
| Publication Date | 2019 Jul;52(4):e12604 |
| PubMed | 31069891 |
| PubMed Central | PMC6668975 |
| DOI | 10.1111/cpr.12604 |