Generation of two induced pluripotent stem cell lines from patients with unbalanced translocation (3;22)


Here we describe the generation and characterization of the human induced pluripotent stem cell (iPSC) lines from urine-derived cells (UCs) from two patients with unbalanced chromosomal translocation t(3,22)(q28;q13.3). The iPSC lines retain the original chromosome abnormality, express pluripotency markers and bear differentiation potential. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.

Authors Ma Y, Zhang H, Yang X, Li Y, Guan J, Zhang K, Huang Y, Pan G, Gai Z, Liu Y
Journal Stem cell research
Publication Date 2019 Oct;40:101545
PubMed 31472451
DOI 10.1016/j.scr.2019.101545

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