Generation of two induced pluripotent stem cell lines from patients with unbalanced translocation (3;22)
Summary
Here we describe the generation and characterization of the human induced pluripotent stem cell (iPSC) lines from urine-derived cells (UCs) from two patients with unbalanced chromosomal translocation t(3,22)(q28;q13.3). The iPSC lines retain the original chromosome abnormality, express pluripotency markers and bear differentiation potential. Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.
| Authors | Ma Y, Zhang H, Yang X, Li Y, Guan J, Zhang K, Huang Y, Pan G, Gai Z, Liu Y |
|---|---|
| Journal | Stem cell research |
| Publication Date | 2019 Oct;40:101545 |
| PubMed | 31472451 |
| DOI | 10.1016/j.scr.2019.101545 |