iPS cell-derived corneal endothelial cell substitutes for bullous keratopathy

General Information

Clinical trials phase Not applicable
Start date (estimated) 2021-07-15
Clinical feature
Label bullous keratopathy
Link http://purl.obolibrary.org/obo/DOID_11031
Publications

Administrative Information

ICTRP weblink https://trialsearch.who.int/Trial2.aspx?TrialID=JPRN-jRCTa031210199
Other study identifiers
Name jRCTa031210199
Description Japan Registry of Clinical Trials (jRCT)
Source weblink https://jrct.niph.go.jp/en-latest-detail/jRCTa031210199
Sponsors Shimmura Shigeto

Cells

Which differentiated cell type is used
Label corneal endothelial cell
Link http://purl.obolibrary.org/obo/CL_0000132
Description An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier.

Recruitment

Recruitment Status Not yet recruiting
Comment recruitment status Pending
Estimated number of participants 3